{"id":1906,"date":"2024-07-10T09:52:27","date_gmt":"2024-07-10T08:52:27","guid":{"rendered":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/?p=1906"},"modified":"2024-07-10T09:54:13","modified_gmt":"2024-07-10T08:54:13","slug":"syndrome-de-deficit-en-glut1","status":"publish","type":"post","link":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/syndrome-de-deficit-en-glut1\/","title":{"rendered":"Syndrome de D\u00e9ficit en GLUT1"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"1906\" class=\"elementor elementor-1906\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6606fde e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"6606fde\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5f6d921 elementor-widget elementor-widget-image\" data-id=\"5f6d921\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 26-05-2024 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"325\" src=\"https:\/\/www.rmsb.u-bordeaux.fr\/wp-content\/uploads\/2024\/07\/GLUT1-1024x325.png\" class=\"attachment-large size-large wp-image-1907\" alt=\"\" srcset=\"https:\/\/www.rmsb.u-bordeaux.fr\/wp-content\/uploads\/2024\/07\/GLUT1-1024x325.png 1024w, https:\/\/www.rmsb.u-bordeaux.fr\/wp-content\/uploads\/2024\/07\/GLUT1-300x95.png 300w, https:\/\/www.rmsb.u-bordeaux.fr\/wp-content\/uploads\/2024\/07\/GLUT1-768x244.png 768w, https:\/\/www.rmsb.u-bordeaux.fr\/wp-content\/uploads\/2024\/07\/GLUT1.png 1506w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-54a8f8f e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"54a8f8f\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3ab4e73 elementor-widget elementor-widget-text-editor\" data-id=\"3ab4e73\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 26-05-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>Le syndrome de d\u00e9ficit en GLUT1 est une neuropathologie p\u00e9diatrique. Elle est caract\u00e9ris\u00e9e par une enc\u00e9phalopathie \u00e9pileptique pharmacor\u00e9sistante, une microc\u00e9phalie inconstante, un retard de d\u00e9veloppement et des troubles moteurs complexes. Son incidence est largement sous-estim\u00e9e. \u00bc des patients ne r\u00e9pond pas au r\u00e9gime c\u00e9tog\u00e8ne, r\u00e9gime riche en graisses, prise en charge standard de la pathologie.<\/p><p>C\u2019est dans ce contexte que le Dr H\u00e9l\u00e8ne Roumes a obtenu un financement de la <b>Fondation pour les Maladies Rares<\/b>, afin de d\u00e9velopper un nouveau mod\u00e8le de la pathologie chez le rat (rat g\u00e9n\u00e9tiquement modifi\u00e9 pour le transporteur au glucose GLUT1) ainsi qu\u2019une subvention du <b>Fond de dotation <\/b><b>Neuroglia<\/b> pour financer une th\u00e8se sur le sujet.<\/p><p>Ce projet est soutenu par les Association sur le Syndrome de D\u00e9ficit en GLUT1 et \u00c9pilepsie France.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Le syndrome de d\u00e9ficit en GLUT1 est une neuropathologie p\u00e9diatrique. Elle est caract\u00e9ris\u00e9e par une enc\u00e9phalopathie \u00e9pileptique pharmacor\u00e9sistante, une microc\u00e9phalie inconstante, un retard de d\u00e9veloppement et des troubles moteurs complexes. Son incidence est largement sous-estim\u00e9e. \u00bc des patients ne r\u00e9pond pas au r\u00e9gime c\u00e9tog\u00e8ne, r\u00e9gime riche en graisses, prise en charge standard de la pathologie. C\u2019est dans ce contexte que le Dr H\u00e9l\u00e8ne Roumes a obtenu un financement de la Fondation pour les Maladies Rares, afin de d\u00e9velopper un nouveau mod\u00e8le de la pathologie chez le rat (rat g\u00e9n\u00e9tiquement modifi\u00e9 pour le transporteur au glucose GLUT1) ainsi qu\u2019une subvention du Fond de dotation Neuroglia pour financer une th\u00e8se sur le sujet. Ce projet est soutenu par les Association sur le Syndrome de D\u00e9ficit en GLUT1 et \u00c9pilepsie France.<\/p>\n","protected":false},"author":5,"featured_media":1907,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[7,6],"tags":[],"_links":{"self":[{"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/posts\/1906"}],"collection":[{"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/comments?post=1906"}],"version-history":[{"count":4,"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/posts\/1906\/revisions"}],"predecessor-version":[{"id":1911,"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/posts\/1906\/revisions\/1911"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/media\/1907"}],"wp:attachment":[{"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/media?parent=1906"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/categories?post=1906"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rmsb.u-bordeaux.fr\/fr\/wp-json\/wp\/v2\/tags?post=1906"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}